News, stories and events concerning EPO

From Griffonia simplicifolia, an aid to control mood and appetite
In spring, many people experience mood swings and sleep disturbances: the sudden increase in daylight and temperatures has an impact on the sleep-wake cycle; it is also the season when the consequences of a heavier diet and sedentary lifestyle typical of the cold season become evident. Let’s discover together a tropical plant that can help us. An African bean naturally rich in 5-hydroxytryptophan Griffonia simplicifolia[...]
An aid against periodontal diseases by PLANoràl®
Periodontal diseases are among the 6 most common non-communicable diseases worldwide. In particular, gingivitis, a mild inflammation of the gums, which, if left untreated, may progress to more serious periodontitis, according to a survey conducted by the GfK research institute and sponsored by GSK Consumer Healthcare, affects approximately 23 million Italians. Symptoms and causes of gingivitis and periodontitis Gingivitis is the mildest form of periodontal[...]
Scientific naming of plants: origin and importance
Formal botanical names are used as the “lingua franca” for a unique identification of plants worldwide. Essentially, it is their scientific designation, established after the taxonomic classification process. It enables the identification of a plant irrespective of vernacular names, which vary from one language to another or even from one region to another within the same country. Today, the rules of botanical naming are established[...]
An aid against stress from the extract of Scutellaria lateriflora L.
Fatigue, mood swings, headaches, insomnia, weight changes and other common symptoms of stress are affecting more and more people around the world: according to a study by Assosalute before the pandemic, 85% of Italians had stress-related disorders; on the other hand, the WHO (World Health Organization) has estimated anxiety-related disorders to be the most common mental disorders worldwide. The Covid-19 pandemic, with its economic and[...]
Scutellaria lateriflora L.: a hydroethanolic extract, chemically characterized, as a possible nutraceutical ingredient in cortisol-mediated stress response
A new in vitro study published in January 2024 in the scientific journal Molecules shows for the first time that a chemically characterized extract of Scutellaria lateriflora L. (BlueCALM®) may be an ideal candidate as a nutraceutical ingredient for relaxation and sleep, due to its significant inhibitory action on the release of cortisol, the so-called ‘stress hormone’. The study employed an in vitro model in[...]
Adaptogen plants: a help for psychophysical homeostasis
The cold weather and reduced daylight typical of winter are external stress factors that act on our bodies. Internal imbalances such as disorders in diet and sleeping, anxiety and fatigue can also play a similar role. Such conditions can disrupt the self-regulation capacity of our body, which naturally tends to a state of stability. When homeostasis is challenged by imbalances of various origins, our bodies[...]
Possible role of a blend of plant extracts of Cistus incanus L. and Castanea sativa Mill. in H. pylori gastric discomfort
A new in-vitro study published in the scientific journal Foods in December 2023 shows that the combination of Cistus x incanus L. and Castanea sativa Mill. (Gastalagin®) may be an ideal candidate to counteract gastric discomfort due to H. pylori, a bacterium that, according to literature sources, is present in 50% of the human population. Plants of the genus Cistus have traditionally been used in[...]
Happy holidays from EPO
The EPO team wishes you happy holidays and a Happy New Year! Our offices will be closed from 23rd December to 7th January. All the requests received during this period will be processed as soon as we are back. In the meantime, you can contact us at for any urgent request.
Nicotine residues in spices: EFSA has just completed the risk assessment
Nicotine is the main alkaloid in tobacco and its harmful effects on smokers, apart from addiction and habituation, are well known. However, not everyone knows that, in addition to tobacco, nicotine is also found naturally and in low concentrations in other plants of the Solanaceae family – such as the tomato, potato, aubergine and bell pepper – where it plays a defensive function against pests[...]
Strengthening the body's natural defenses and preparing for the cold season through proper nutrition and botanicals
Seasonal changes are periods of the year when our immune system is more vulnerable. There isn’t a single cause for coughs, flu, sore throats, and other autumnal illnesses, but a combination of factors to take into account. Cold weather and the decrease in natural daylight hours during the day, which promotes more sedentary behavior, while not directly responsible for seasonal illnesses, can undoubtedly contribute to[...]
Medicinal and aromatic plants: cultivation or wild collection?
According to an analysis by Fortune Business Insights, the global herbal medicine market will grow from USD 165.66 billion in 2022 to USD 347.50 billion by 2029. This is unprecedented growth, not least as a consequence of the Covid-19 pandemic, when people turned to traditional medicine to defend themselves against the infection. However, from 2001 to 2014, the global market for medicinal plants (MAP) had[...]
Hyperpigmentation, dark spots on the skin and natural remedies
Hyperpigmentation is a skin imperfection consisting of dark spots of varying size, caused by an overproduction of melanin, the skin pigment also responsible for tanning. According to data from an Ipsos market research study, skin hyperpigmentation affects more than 54 percent of women between 20 and 60 years of age and, particularly on the face, is perceived as the third most common aesthetic nuisance, after[...]
Happy holidays from EPO
We are taking a break to recharge our batteries and come back more energetic than before. Our offices will be closed from 7th to 18th August. In the meantime, you can contact us at for any urgent requests. We wish everyone a happy and relaxing holiday!
Plant extracts and sweating: an aid from nature for regulating a vital function
Sweating is a physiological mechanism through which our body emits a liquid produced by sweat glands in order to regulate body temperature and perform other functions, such as excreting ‘waste’ substances or non-verbal communication. However, while it is normal to sweat a little more than usual when it is hot, and it is normal to sweat a lot more than usual when engaging in strenuous[...]
Dyeing plants: a centuries-old tradition returning as a sustainable solution
Why has man, since prehistoric times, sought to surround himself with color? Where did he find the material in nature to meet a need so deep-rooted in his soul? The art of extracting colors from natural resources has roots that go back to the dawn of mankind, but with the advent of synthetic dyes – which are cheaper and more versatile – the knowledge associated[...]
Nickel in food: European Commission intends to set limits
In March, the European Commission launched a public consultation in order to receive comments in relation to a proposal aimed at introducing maximum levels of nickel in foodstuffs; at present, nickel is not regulated by Regulation (EC) 1881/2006, now replaced by Regulation (EU) 915/2023, which comes into force on 25/05/2023. As early as 2020, EFSA (the European Food Safety Authority) expressed concern about the presence[...]
Plant extracts from Cistus incanus L. and Scutellaria lateriflora L.: their combination has antimicrobial and antibiofilm properties, preventing periodontal diseases
A new study published in the scientific journal Foods shows that the combination of Cistus incanus L. and Scutellaria lateriflora L. (PLANoràl®) has promising and useful effects for the treatment of gingivitis and for the eubiosis of the oral cavity. These plant extracts contain a very complex mix of polyphenols, stable after simulated in vitro oral digestion, and, when combined into a patented blend, show[...]
Seasonal allergies: how to deal with them using plant extracts
The arrival of fine weather entices us to spend more time outdoors, but for seasonal allergy sufferers, even a simple walk in the park can turn into the worst nightmare. Allergies are among the most prevalent chronic diseases worldwide; according to the Italian National Institute of Health (ISS), the prevalence of allergic rhinitis is steadily increasing: in Europe, it is estimated at between 10 and[...]
Ellagitannins from Castanea sativa Mill.: chestnut leaf extracts have specific antibacterial action against Helicobacter pylori and reduce inflammation in human gastric epithelial cells
A new study published in the scientific journal Nutrients shows that two ellagitannins contained in chestnut leaves play an important role in the interaction between H. pylori and human gastric epithelium; these bioactive molecules have also been shown to have anti-inflammatory properties through an inhibition of the NF-kB factor, that plays a key role in regulating the response to infection. That provides, for the first time,[...]
New EU Regulation 2022/1370 to limit consumption of ochratoxin A
On August 5th, 2022, the European Commission issued the new EU Regulation 2022/1370, updating the previous EC Regulation 1881/2006, and amended the list of foodstuffs that contribute to human exposure to ochratoxin A. Underlying this decision is concern about the intake of foodstuffs, contaminated with this mycotoxin, in quantities potentially dangerous to human health. Read on to find out about the consequences of EU Regulation[...]
A new frontier: the use of botanicals as "green" raw materials in industry and artwork restoration
The use of botanicals as “green” raw materials in industry and art restoration is part of the growing focus on the environment and the use of “eco-friendly” strategies, in line with the challenges of the UN 2030 Agenda. Since the dawn of mankind, medicinal plants have been used to improve the health of humans and animals. However, botanicals can also be used in contexts other[...]
New regulation on green tea extracts containing EGCG
A new European Union regulation limits the amount of green tea extract containing epigallocatechin gallate (EGCG) that can be present in food and sets new labeling requirements.  Underlying this decision are health concerns related to EGCG, a catechin responsible for potential liver damage. Continue reading to find out the consequences of the regulation that went into effect on December 22, 2022, and the measures we[...]
Merry Christmas from EPO
The EPO team is wishing you a Happy Holiday and a joyful New Year! We wish to inform you that our offices will be closed from December 24th until January 8th due to the Christmas holiday season. All inquiries received during this time will be processed as soon as we return. Please email in case of need.
A taste of Christmas: botanical extracts for food and beverage
Cinnamon, ginger, vanilla, and star anise are the traditional flavors of Christmas. Where do these natural extracts come from and how are they used in food and beverage preparations? Find out in this article. Botanical extracts for the food industry Today, consumers are more interested in products with natural ingredients that can support a healthy and balanced lifestyle. Botanical extracts play an essential role in[...]
What future for global biodiversity?
Recently, the release of the WWF Living Planet Index 2022 turned the spotlight back on the health of global biodiversity. Let’s take a look at the findings that emerged from the report and the most significant threats facing living species.  Living Planet Index, a snapshot of biodiversity The Living Planet Index is an index developed by WWF that measures the relative abundance of vertebrate species[...]
Natural solutions to boost your immune system
As cold weather arrives, we get more concerned about our health. Spending a lot of time indoors increases exposure to viruses and bacteria, which cause respiratory tract infections, from seasonal flu to the now-established COVID-19. To defend ourselves against illness, we need an efficient immune system, as well as a healthy lifestyle and a balanced diet to support our immune response.  Understanding the immune system[...]
Natural ways to stay healthy during season change
With the arrival of the cold season, our mental and physical well-being can be challenged. Fewer daylight hours and cooler temperatures can lead to a sense of depression and general discomfort, which is described as seasonal affective disorder (SAD). Let’s explore what it is, as well as the best natural remedies to address the season change.  Seasonal affective disorder: causes, symptoms, and distribution The climatic[...]
An overview on pyrrolizidine alkaloids: the risks for human health
Natural substances and health do not always go hand in hand. Such is the case with pyrrolizidine alkaloids (PA), a group of alkaloids derived from pyrrolizidine that includes compounds highly toxic to humans. Let’s find out more about them.  What are pyrrolizidine alkaloids and where to find them? Pyrrolizidine alkaloids are produced by plants to defend themselves against pests and herbivores and have been identified[...]
Natural antioxidants and their health benefits
Think about holidays, the sea, the sun… Behind the pleasant sensations evoked by these images lie potential threats, particularly for the skin.  It is widely known that exposure to the sun’s UV rays increases the production of free radicals, unstable and highly reactive molecules that, if not adequately counteracted, can damage the skin at the cellular level. The consequences can be the loss of tissue[...]
Happy holidays from EPO!
The summer holidays are upon us: it’s time to take a break and collect some soothing memories. Our offices will remain closed from 8th to 19th August. For general enquiries, please contact
5 ways to start a sustainable business transition
When talking about sustainable transition, we are referring to the need for a radical transformation of society toward goals of equity and harmony with the Planet. Climate change, social inequality, and the risk of new pandemics are merely a few of the global crises that lie ahead. Rather than standing by, both individuals and businesses are called upon to do their part.  In recent years,[...]
Botanicals for digestive disorders and Helicobacter pylori infection
People have always resorted to botanical remedies to alleviate symptoms of common health problems and regain mental and physical well-being. Disorders related to gastric discomfort are no exception: hyperacidity, heartburn, nausea, and sickness affect 70% of the adult population.  Digestive disorders: an overview Stress, poor diet, alcohol consumption, drug intake, age, and a hectic lifestyle are among the leading causes of digestive disorders, which, if[...]
How the Russia-Ukraine war is impacting global supply chains
The tragic turn of events in Ukraine is once again threatening the global economy, with devastating consequences on supply chains.  As TV news brings back scenes that we hoped to never see again, the effects on the lives of people and businesses around the world are already evident: rising inflation, possible supply disruptions, and raw material shortages.  Just think of the consequences on the food[...]
Coping with anxiety in times of crisis: a help from nature
According to the World Health Organization, the global prevalence of anxiety and depression increased by 25% in the first year of the pandemic. While the COVID-19 emergency continues, the situation is likely to get worse as a result of the Russian-Ukrainian war.  Mental health in the COVID-19 pandemic Over the past two years, demand for food supplements for anxiety and sleep disorders has peaked. Since[...]
Shaping an inclusive market: Kosher, Halal and Vegan certifications
Transparency and inclusiveness are increasingly central aspects in the eyes of consumers. Reading the label of a product, be it food, cosmetics, or clothing, is often not enough to reassure about the origin of the ingredients it contains. The demand for sustainable products is a trend that will drive market growth in the coming years. On the other hand, in a multi-ethnic society, companies are[...]
Pets and the Pandemic: How the Lockdown Led to an Adoption Boom
One of the most surprising side effects of the pandemic was the boom in pet adoptions seen during the early months of lockdown. Dogs and cats have helped their owners cope with feelings of anxiety and isolation linked to the spread of the COVID-19 virus. At the same time, an increased concern for the health and nutrition of our furry friends is leading to the[...]
Anticholesterolemic Activity of Three Vegetal Extracts (Artichoke, Caigua, and Fenugreek) and Their Unique Blend
A new study published in Frontiers in Pharmacology confirms the anticholesterolemic efficacy of vegetal extracts of artichoke, caigua, and fenugreek and their unique blend. Liver lipid and cholesterol dysregulation are recognized as a major cause of cardiovascular diseases. In this respect, nutraceutical formulations with anticholesterolemic activity like our OMEOlipid extract could be instrumental in hypercholesterolemia prevention and treatment, representing a valid alternative to current therapies[...]
Ten Books to Read for Plant Lovers
Thinking of snuggling up with a book this winter? With the holiday season knocking at the door, staying in with a good reading and a steaming cup of tea is an exquisite pleasure. Here you will find ten book recommendations for botany lovers: our reading list includes both classic and contemporary books, to explore the plant universe and its connections with other worlds, from history[...]
Promoting biodiversity and local supply chains: EPO’s commitment
The relationship between living beings and their environment is both complex and fragile. In a world undergoing profound change, ensuring the survival of the species and the harmony between humans and nature has become increasingly crucial. For years, our company has been working in line with the Sustainable Development Goals of the UN 2030 Agenda, to reduce the environmental impact of our production and guide[...]
Thymus vulgaris Essential Oil and Hydro-Alcoholic Solutions to Counteract Wooden Artwork Microbial Colonization
The sustainable conservation of historic-artistic artifacts requires eco-compatible and non-toxic products, safe for both the environment and human health. In this study published on Applied Sciences, our Scientific Director Giovanna Nicotra and R&D Analyst Beatrice Bruno took part in a research on the use of Thymus vulgaris extract to counteract microbial colonization on wooden artwork. Decay, bacteria, fungi, and insects represent a threat to the[...]
Healthy mouth, healthy body: the link between oral health and systemic diseases
The mouth is responsible for many daily actions, from nutrition to language and social interaction. For this reason, oral health deeply influences the quality of life: dental and periodontal pathologies such as periodontitis can affect the body as a whole.  In this article, we will shed light on the link between oral and systemic health and explore some solutions for preserving the well-being of teeth[...]
Planoràl, synergy in a unique blend
The oral cavity forms an indispensable part of the human microbiome, for its unique and diverse microflora, which includes up to approximately 100 species of bacteria, fungi, viruses, archaea and protozoa. Some of these bacteria are implicated in the pathogenesis of oral diseases such as caries and periodontitis; Porphyromonas gingivalis is a main etiological factor in periodontal diseases. EPO’s new patented extract Planoràl is a[...]
Protecting botanicals from adulteration: the importance of DNA barcoding
A test that uniquely identifies each living species, similarly to a UPC barcode, can ensure the safety and compliance of botanical and herbal products. This is the essence of DNA barcoding, a technique with many important applications, including the fight against adulteration. Discover more in this article.  What is DNA barcoding and how does it work? DNA barcoding is a method of species identification derived[...]
Voice drink with hedge mustard: a recipe from the University of Milan
The singers’ plant: this is the popular name given to hedge mustard, a wild plant found all over Europe. Opera singers have always sung its praises as a miracle remedy for throat disorders. Today, hedge mustard is also used in food preparations, where it stands out for its pungent flavour. In this article, we will shed light on its properties and present a recipe to[...]
Summer holidays EPO
EkinACT: the mountain Echinacea to boost the immune system
The made in EPO extract of Echinacea purpurea (L.) Moench to boost the immune system     Click here to read more and to download the brochure!
Aloe vera: uses, benefits and concerns
Summer is coming, that time of the year when the skin is more exposed to sunlight. The shops are packed with products to prevent and soothe sunburn, like lotions and protective gels, many of them containing aloe vera. In this article we will investigate the properties of this plant, its uses and recent concerns. Traditional uses of aloe vera Aloe vera, Aloe vera (L.) Burm.f.,[...]
Cinnamon Waste Material as Feedstock for the Microbial Production of Carotenoids
Good news for #circulareconomy! According to a study published in the International Journal of Environmental Research and Public Health, Cinnamon waste material could be used to produce carotenoids and high-value molecules for the food, feed, dye, and cosmetic sectors. We are proud to have collaborated in this research project. It is an important finding from a #sustainability perspective, because the valorization of residues allows for[...]
WEBINAR: Botanical extracts in pet food formulations - regulatory framework, benefits and trends
During the webinar we explored the latest trends in the pet food industry and learnt how COVID-19 made it more important than ever to support pet well-being through high-quality pet food formulations and botanical extracts. CLICK HERE TO DOWNLOAD THE SLIDES and don’t forget to WATCH THE VIDEO! The webinar was divided in three parts, each with a specific topic. 1. Complementary feed for pets:[...]
Marshmallow: from tradition to science
click here to download the brochure
Join our webinar: Botanical extracts in pet food formulations
Do you work in the pet food industry and want to keep up to date with the latest trends? EPO Srl is pleased to announce a new webinar in collaboration with Saporiti Consulting. The webinar will focus on ‘Botanical extracts in pet food formulations: regulatory framework, benefits and trends’ and will be held on Wednesday 19th May at 11.30 AM CET.  Click here to register[...]
ENOTprost: from the raw material to the high-quality extract
What is it? ENOTprost is the new extract of Epilobium angustifolium L. standardized to contain 15% Oenothein B, one of the most active compounds of this plant! The botanical species is certified by the DNA barcoding analysis. Why should I use it? Its effects are prostate-specific: anti-inflammatory and antioxidant!  The inflammation and oxidative stress should be fought  and controlled as they are risk factors for the development and[...]
The potential efficacy of EPO’s botanical extracts on dermal toxicity due to jellyfish envenomation
Click here to download this paper (WILDERNESS & ENVIRONMENTAL MEDICINE 2020; 31(3): 266e72)
A new Sicilian pomegranate extract!
An incredible antioxidant and weight loss aid!   Click here to download the scientific article to learn more about its beneficial effects
OMEOLIPID -for lipid metabolism
Omeolipid is an association of Artichoke (Cynara scolymus L.), Caihua (Cyclanthera pedata (L.) Schrad.) and Fenu greek (Trigonella foenum-graecum L.) that can be used in food supplements.   Omeolipid combines the traditions of three different countries: Artichoke is a Mediterranean plant; its cultivation in Europe dates back to ancient Greece and Rome. Its active substances (caffeoylquinic acids, flavonoids, sesquiterpene lactones) are concentrated in the leaf,[...]
Are you sure that you are using the right Cinnamon?
CINNAMON IS NOT ONLY A SPICE! Cinnamon is one of the oldest known herbs: obtained from an exotic tree, indigenous to Sri Lanka and Southwest India, it is mentioned in the Bible as well as in Sanskrit, Egyptian, Greek and Roman texts. Its inner bark, after drying and curling into rolls known as “sticks” or “quills”, is mainly used as a spice, especially in Christmas[...]
Botanicals with adaptogenic effects
Adaptogenic effects of herbal extracts The term ‘adaptogen’ refers to natural compounds or plant extracts that increase adaptability and survival of organisms to stress. They exhibit anti-fatigue effects during stress and show promising potential against age-related conditions. Adaptogens stimulate cellular and organism defense systems by means: – activating intracellular and extracellular signaling pathways and expression of stress-activated proteins and neuropeptides; – enhancing survival against oxidative[...]
COVID 19: WHAT ABOUT PHYTOTHERAPY? The Covid-19 world emergency is leading to an increase of the botanicals’ demand. However, at present, there are no scientific evidences proving the direct activity of botanicals, vitamins and, in general, of food supplements, against coronavirus SARS-CoV-2 infection. Therefore, it is strictly necessary to give proper information when advising products with unproven uses. This monograph is a state-of-the-art overview about[...]
THYMOX - The EPO thyme extract
Thyme (Thymus vulgaris L.) is a well-known Mediterranean plant, belonging to the Lamiaceae family. The thyme extract is traditionally used as natural remedy for cough and for many other purposes, as digestive, spasmolytic, carminative and anti-oxidant. The actives are mainly concentrated in the aerial parts, collected at the blooming time. Thyme contains essential oils (as thymol), tannins, flavonoids and triterpenes. Therefore…download our brochure and do[...]
True science behind EPO extracts
This work was presented at ‘Pharmacology 2019 Congress’ in Edinburgh Download here the ‘book of abstract’ 
High Quality Goji Berry dry extract
High Quality Goji Berry dry extract To wish you well-being and longevity using EPO’s botanicals! Botanical information: Goji berries (Lycium barbarum L.)  belong to the Solanaceae family that yields numerous foods, including potatoes, tomatoes and eggplants. Goji is usually found in Asia, particularly in Northwestern China. The plant is known as kuko in Japan and gugija in Korea, while its common name, Goji, derives from[...]
Have you already thought about the next food supplement for flu and common cold?
Here the right botanicals by EPO Click on each plant to learn more…   Common thyme               English plantain   Lime tree               Sundew               Black Elder  
Botanicals for SKIN CARE
Nature, Tradition and Science serving beauty! Dear Customer, we have selected some extracts to help you to formulate a food supplement for skin care! Botanicals have always been a perfect adjuvant for the beauty of the skin and body. Download here a short monograph and do not hesitate to contact us for more information.   EPO Team 
Close modal
Signup Newsletter